If you have any questions, please use our Contact Form.
You can also order by e-mail: info@bioevoly.com
Larger quantity required? Request bulk
| Species: | Human |
| Protein Construction: | IL-1α (Ser113-Ala271) Accession # P01583 |
| Purity: | > 97% as analyzed by SDS-PAGE > 97% as analyzed by HPLC |
| Endotoxin Level: | < 1 EU/μg of protein by LAL method |
| Biological Activity: | Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 1.0 pg/ml, corresponding to a specific activity of > 1.0 × 109 IU/mg. |
| Expression System: | E. coli |
| Theoretical Molecular Weight: | 18 kDa |
| Formulation: | Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4. |
| Reconstitution: | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. |
| Storage & Stability: | Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles. |
| Target Background: | IL-1 alpha is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1 beta is a secreted cytokine, IL-1 alpha is predominantly a cell-associated cytokine. |
| Synonyms: | IL1A; IL-1A; IL1; IL1-ALPHA; IL1F1; interleukin 1 alpha; IL-1 alpha; IL-1α |
For more documents, please visit "Technical Support".
Thanks for subscribing!
This email has been registered!
| Product | SKU | Description | Collection | Availability | Product Type | Other Details |
|---|
